Title: AGAP2-AS1 regulates AGAP2 mRNA levels Abstract: AGAP2-AS1 is an antisense lncRNA situated in the 3’ end of AGAP2. It is becoming now more widely accepted that 3’ antisense lncRNAs can modify the expression of their gene counterparts and we demonstrate here that this is the case as well for the tandem AGAP2 – AGAP2-AS1.
2021-02-15
Long Non-Coding RNA AGAP2-AS1/miR-628-5p/PTN Axis Modulates Proliferation, Migration, Invasion, and Apoptosis of Glioma Cells Browse information about AGAP2-AS1 (ENSG00000255737) covering related drugs, protein structure, pathways, genetic associations, orthologs, RNA expression and cancer biomarkers. Your search resulted in multiple matches. Please select a position: Gencode Genes AGAP2-AS1 (ENST00000542466.2) at chr12:57726271-57728356 - Homo sapiens AGAP2 antisense RNA 1 (AGAP2-AS1), long non-coding RNA. 3 Dec 2020 Clinically, increased expression of serum AGAP2-AS1 predicts poor response to trastuzumab treatment in breast cancer patients. In conclusion, 2 Mar 2021 LncRNA AGAP2-AS1 Promotes Cancer Cell Proliferation, Migration and Invasion in Colon Cancer by Forming a Negative Feedback Loop with 2 Mar 2021 LncRNA AGAP2-AS1 Promotes Cancer Cell Proliferation, Migration and Invasion in Colon Cancer by Forming a Negative Feedback Loop with HGNC data for AGAP2-AS1. Approved symbol. AGAP2-AS1. Approved name.
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11 In gastric cancer, SP1 activates AGAP2-AS1 to increase cancer cell migration and proliferation. 12 In breast cancer, overexpression of AGAP2-AS1 regulates the methylation of MyD88 to promote the development of chemoresistance. 13 … 2021-01-01 AGAP2-AS1 upregulates the MMP2 expression, we first analyzed the cellular localization of AGAP2-AS1 using immunofluorescence. As shown in Figure 3A, AGAP2-AS1 was localized mainly in the cytoplasm in TPC1 and K1 cells.
>tr|H2N5H1|H2N5H1_PONAB Uncharacterized protein OS=Pongo abelii GN=RUSC1-AS1 PE=4 SV=1
Approved name. AGAP2 antisense RNA 1. Locus type. RNA, long non-coding.
Complete information for SATB2-AS1 gene (RNA Gene), SATB2 Antisense RNA 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
Tous agap2 : notre application interne pour rester connectés. Jérôme M. Rousseau - Responsable de département - agap2 agap2 - Agap2 Agap2-as1. Agap2 Gene · Agap2 Switzerland · Agap2it · Agap2-as1 · Agap2 Netherlands · Agap2 Avis · Agap2 Deutschland · Agap2 Glassdoor · Operation Hydra Case · Srijit Gumamit ng mga kamangha-manghang mga nakasisiglang larawan para sa iyong blog, tumblr, website, portfolio, o anumang pipiliin mong ibahagi. Stunning AGAP2-AS1 (AGAP2 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with AGAP2-AS1 include Glioblastoma and High Grade Glioma.
However, the expression pattern and molecular mechanism of AGAP2-AS1 in gastric cancer (GC) have not been characterized. AGAP2-AS1 was demonstrated as an oncogene in several cancers, including glioblastoma (GBM). However, the biological mechanisms of AGAP2-AS1 in GBM progression are still unclear.
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Diseases associated with AGAP2-AS1 include 18 Sep 2020 The lncRNA AGAP2 antisense RNA 1 (AGAP2-AS1) is Keywords: LncRNA, AGAP2-AS1, papillary thyroid cancer, miR-424-5p, MMP2. with three genes (CTBP1-AS2, OTUD6B-AS1, and AGAP2-AS1) exceeding the study-wide Bonferroni- corrected P-value (PBonf < 0.0023, Pcombined ¼ 1.1 Â OTUD6B-AS1 and AGAP2-AS1) exceeding the study-wide Bonferroni-corrected ρ-value. 96. (PBonf<0.0023, Pcombined = 1.1x10-9, 1.4x10-8, 1.7x10-6, 2, AGAP2-AS1 (AGAP2 Antisense RNA 1), miR-16-5p, ANXA11, 31088485. 3, AK054386, miR-199, None specified, 31827704.
Knockdown of AGAP2-AS1 inhibited the proliferation
Therefore, si-AGAP2-AS1 1, 2 and pcDNA-AGAP2-AS1 were used for all subsequent AGAP2-AS1 knockdown or overexpression experiments. SP1 induces high expression of AGAP2-AS1 According to the article and prediction, we found that the transcription factor SP1 may induce the high expression of AGAP2-AS1 (Dong et al. 2018 ). AGAP2-AS1 promoted cell growth, suppressed apoptosis, and caused trastuzumab resistance, whereas knockdown of AGAP2-AS1 showed an opposite effect.
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AGAP2‐AS1 can be activated by transcript factor FOXP1. A and B, FOXP1 expression level at protein and RNA level by Western blotting and qPCR, respectively, when HTR‐8/SVneo cells were transfected with FOXP1‐specific siRNAs. The AGAP2‐AS1 expression level was tested by qPCR after treated with siRNAs against AGAP2‐AS1 (B, right panels).
Taken together, AGAP2-AS1 knockdown exercises suppressive effects on the development of EC through miR-195-5p-dependent downregulation of FOSL1. Select categories you would like to watch. Updates to this gene will be send to {{ username }} AGAP2-AS1 was demonstrated as an oncogene in several cancers, including glioblastoma (GBM).
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Sigma-Aldrich offers abstracts and full-text articles by [Huaying Dong, Wei Wang, Shaowei Mo, Ru Chen, Kejian Zou, Jing Han, Fan Zhang, Jianguo Hu].
(B) AGAP2-AS1 decreased in OC tissues compared to ovarian borderline tumors (P < 0.05, Student's t-test). AGAP2-AS1 demonstrated higher expression in tumor tissues compared with normal tissues (P<0.001; Fig. 1A). Additionally, the expression of AGAP2-AS1 was analyzed in 72 pairs of ccRCC tissues and non-cancerous adjacent tissues using Wilcoxon singed-rank test. Title: AGAP2-AS1 regulates AGAP2 mRNA levels Abstract: AGAP2-AS1 is an antisense lncRNA situated in the 3’ end of AGAP2.
AGAP2-AS1 (AGAP2 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with AGAP2-AS1 include Glioblastoma and High Grade Glioma. Additional gene information for AGAP2-AS1 Gene HGNC (48633)
Mechanistically, AGAP2-AS1 is associated with HuR, and the AGAP2-AS1–HuR complex could directly bind to the CPT1, increasing its expression via improving RNA stability. In addition, AGAP2-AS1 AGAP2-AS1 has 521 functional associations with biological entities spanning 3 categories (chemical, cell line, cell type or tissue, gene, protein or microRNA) extracted from 15 datasets. Click the + buttons to view associations for AGAP2-AS1 from the datasets below. If available, associations are ranked by standardized value The lncRNA AGAP2-AS1 is located on a cytogenetic band in chromosome 12q14.1, which contains 1567 nucleotides (12q14.1 is the gene symbol of AGAP2-AS1 in HUGO Gene Nomenclature Committee 48633, entrez gene: 100130776, Ensemble: ENSG00000255737). Long non-coding RNA (lncRNA) AGAP2-AS1 acts as an oncogene in several types of cancers.
Journal of Cell Science. 118 (Pt 15): &n AGAP2-AS1 Silencing Inhibits Proliferation, Migration, and Invasion but Promotes Apoptosis of EC Cells by Decreasing FOSL1 Expression via. Upregulation of 12, ENSG00000229950, TFAP2A-AS1, 1.70E-15, 8.59E-13, 1.89.